I would definitely say that having his head blown off, which it was, would kill him no matter what. BUT, I can also see him surviving a rocket to the face in his usual state. I would assume a rocket would hit his face, and kind of ricochet off or slide off and keep going. If it exploded I see it just knocking him way back and stunning him. We have to admit. In his regular form, Wesker was a goddamn badass. And I would argue that he was the most powerful being in the RE universe. I'd argue that to my grave.

I meant badass as in how the hell do you kill this man??? What is he??? That kind of way. As for Alex, he may indeed turn out to be better, but for now I say Albert wins everything. Non-Uruburos Albert anyway, as you mentioned. Have you ever wondered if these guys and unmutate after they mutate? Like Saddler...I just don't understand how he would cram all that back into a human lol.

Wesker was playing around and Chris and Jill were still no match. He is also extremely strong. At least as strong as Nemesis. He plucked that missile up like it was nothing. Plus he is extremely intelligent. And wayyyy faster than anything else in the series.

Look at Wesker's survivability. He's the main guy. The big one. I think logically he is the most powerful being.